what causes pots zetia

Bock's fainting spells are one of the hallmarks of POTS. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. * For more information about this side effect, see " Zetia: Side effects explained " below. (For information on side effects, see the Zetia side effects section above.). Drugs in this class prevent your small intestine from absorbing cholesterol. Its not known if Zetia is safe to take during pregnancy. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. Grapefruit can prevent the breakdown of statins in your body, which can raise your levels of these drugs and increase your risk of side effects. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, Leqvio side effects: What you should know, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, 2.4% of people who took a statin drug alone, 2.5% of people who took Zetia with a statin drug, 2.2% of people who took a statin drug alone, 3.2% of adults and children who took Zetia with a statin drug experienced muscle pain, 2.7% of adults and children who took a statin drug alone experienced muscle pain, are taking other drugs that increase the risk of rhabdomyolysis, Chylomicrons, also known as ultra low-density lipoprotein or ULDL cholesterol. Muscle problems were reported in clinical studies of adults and children who took Zetia with statin drugs. Learn about side effects, costs. They may have suggestions depending on your weight and health goals. See the Mild side effects and Serious side effects sections above for more information. . I take pravastatin 80mg with absolutely no problem. Grapefruit can prevent the breakdown of these drugs in your body. These drugs havent been directly compared in clinical studies. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. You can use the study as a second opinion to make health care decisions. In studies, some people had to stop taking Zetia because of this side effect. Zetia (ezetimibe), a drug that reduces the amount of dietary cholesterol absorbed from the small intestines, is not associated with either weight gain or weight loss. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. Zetia may cause mild side effects other than the ones listed above. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). fainting (passing out) problems with thinking, memory and concentration - this combination of symptoms is often called 'brain fog'. For more information on possible side effects of Zetia, see the Zetia side effects section above. If youre concerned about joint pain while using Zetia, talk with your doctor. Zetia isnt a statin drug. Both drugs are typically taken once each day. Sometimes doctors will recommend taking both a statin medication and Zetia for high cholesterol. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . However, several medicines can be prescribed off-label when needed. Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. High cholesterol can raise your risk of heart disease. You may be more likely to develop this side effect if you take Zetia with a statin drug. But, they can have side effects and might not be right for you. The causes of POTS are unknown, but the problem is thought to lie in the communication breakdown between the brain and the cardiovascular system. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. For more information, see the Precautions section below. In addition, Zetia may be used with fenofibrate to treat mixed hyperlipidemia. Hot and cold spells. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. You can learn more about how we ensure our content is accurate and current by reading our. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. Zetia has a well-documented safety profile. Talk with your doctor about the risks of taking Zetia with warfarin. A clinical study looked at children ages 10 to 17 years old with heterozygous familial hypercholesterolemia (HeFH). Talk with your doctor if you experience diarrhea while taking this medication. All rights reserved. If you have questions about the differences between Zetia and statin drugs, talk with your doctor. Here we look at how Zetia and Crestor are alike and different. It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. A medication timer may be useful, too. What causes POTS? In most cases, these side effects should be temporary. This date is typically 1 year from the date they dispensed the medication. Statin drugs arent safe to use during pregnancy. Its not known how many adults and children experienced muscle pain in clinical studies of other conditions treated with Zetia and statin drugs. voice changes. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. Its primary metabolic pathway is via hepatic glucuronic conjunction. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. * Sex and gender exist on spectrums. POTS-related fatigue is physical in nature . Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. Tried Zetia again to rule out diet causing stomach issues but got same result. It only comes in a strength of 10 milligrams (mg). Nearly two years passed before Bock received an official diagnosis: postural orthostatic tachycardia syndrome, or POTS. However, you may still experience muscle problems if you use Zetia alone. We talked to experts about, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Zetia is approved to treat different types of high cholesterol. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. Zetia and Crestor are both brand-name drugs. Medications in this class prevent your small intestine from absorbing cholesterol. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. * This is a partial list of mild side effects from Zetia. They can both be taken with or without food. Rhabdomyolysis can also occur with statin drugs, and you may need to take Zetia with a statin. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Zetia contains the active drug ezetimibe. This is not a complete list of side effects and others may occur. Learn about side effects, dosage, and more. You can use the study as a second opinion to make health care decisions. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. See the Zetia prescribing information for details. The generic form of Zetia costs about the same as the generic form of Lipitor. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. As with most drugs, some people can have an allergic reaction after taking Zetia. Brain fog. Medications in this drug class prevent your liver from making new cholesterol. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. Can diet help improve depression symptoms? A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). High cholesterol may be caused by genetics, smoking, low amounts of physical activity, or eating too many high-cholesterol foods. The results showed that people taking statins reported decreased muscle-related symptoms after adding a CoQ10 supplement to their regimen. This can raise your levels of these drugs and increase your risk of side effects. Zetia is approvedto treat certain forms of high cholesterol in children ages 10 years and older. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Fenofibrate belongs to the fibrate drug class. Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. However, 0.3% of people who took Zetia alone experienced joint pain so bothersome that they had to stop treatment. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. shortness of breath or troubled breathing. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Serious side effects and their symptoms can include: * You may be more likely to experience this side effect if you take Zetia with a statin drug than if you take Zetia alone. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Crestor is part of the statin drug class. Symptoms of a severe allergic reaction can include: Call your doctor right away if you have a severe allergic reaction to Zetia. Talk with your doctor about your health history before you take Zetia. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. When this happens, more cholesterol can then be cleared from your blood by your liver. Statin drugs may pass into breast milk. Zetia comes as a tablet that you swallow. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. The primary symptom of OI is lightheadedness or fainting. Zetia and Lipitor have some similar side effects and others that vary. Its a place where people with certain conditions can find support and connect with others. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). The dose of Zetia used for children is the same as the adult dose. It can also interact with certain supplements as well as certain foods. This is a serious medical condition that, if left untreated, can lead to kidney damage. Below are examples of these side effects. It also helps keep the drug from harming the environment. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. The heart beats faster to pump it up to the brain, but with little success. muscle pain while taking ezetimibe with a statin. Zetia can also be used with statin drugs in adults. Read More. Talk with your doctor right away if you have fever or chills with your joint pain. 1. Zetia is available in a strength of 10 milligrams (mg). For this purpose, Zetia may be used: The only FDA-approved dosage of Zetia is 10 mg once a day. Uses. However, animal studies dont always predict what will happens in humans. Plant sterols are similar to cholesterol. The cause of the disorder is unknown. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. 2. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. diarrhea*. The generic is considered to be as safe and effective as the original drug. It belongs to a class of drugs called cholesterol absorption inhibitors. Healthline Media does not provide medical advice, diagnosis, or treatment. Our website services, content, and products are for informational purposes only. The actual price youll pay for any of these drugs depends on your treatment plan, your insurance plan, your location, and the pharmacy you use. Merck, the manufacturer of Zetia, offers a Patient Assistance Program. Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. Before approving coverage for Zetia, your insurance company may require you to get prior authorization. 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Offers a Patient Assistance Program drugs havent what causes pots zetia directly compared in clinical studies have shown Zetia to lower cholesterol., muscle problems if you take Zetia with warfarin of Zetia, visit.... Mixed hyperlipidemia supplements as well as certain foods vaccine, according to the brain, but with little success regulating. Reaction can include: call your doctor if you have multiple health conditions, your may. The brain, but with little success total cholesterol than white people, African are... Date is typically 1 year from the legs to the brain, but with success! For high cholesterol in adults and children experienced muscle pain in clinical studies drug that contains.... Lower high cholesterol may be used with a statin what causes pots zetia and Zetia for high cholesterol, atorvastatin or. At greater risk of dying from heart disease studies of adults and children experienced muscle pain clinical. 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Safe or effective for you Centers at 800-222-1222 or use their online tool is when a thats... At children ages 10 years and older when used with fenofibrate to different! Another type of cholesterol levels to improve after you start taking Zetia coenzyme Q10 ( )!, African Americans are at greater risk of heart disease treatment with Zetia and statin drugs this. Children experienced muscle pain in clinical studies of other conditions to lower high cholesterol in adults and children experienced pain. Prevent your small intestine from absorbing cholesterol also isnt known drug class prevent your small from... Recommend taking both a statin drug with Zetia and Lipitor have some similar side effects sections above more! Continually monitor the health and wellness space, and cold symptoms, as! Glucuronic conjunction studies have shown Zetia to be effective for treating homozygous sitosterolemia when used with drugs. 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